", "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", Kidney stones and drugs with ingredients of metformin hydrochloride, Kidney stones in Pfizer BioNTech Covid Vaccine, Kidney stones in Johnson and Johnson Covid Vaccine, Hydrochlorothiazide and Chronic Kidney Disease, Metronidazole and Valacyclovir drug interaction, Metoclopramide Hcl and Famotidine drug interaction, Blopress and Intervertebral Disc Degeneration, Darzalex and Chondroitin drug interaction. Insulin is crucial to regulating blood sugar levels. Larger stones may cause a great deal of pain. Video of the Day Metformin is excreted out of the body by the kidneys. If your son has a lot of them he. Went to emergency 6-14 because I was out of my home area. D.D. Other drugs that have the same active ingredients (e.g. They may hurt, but they will pass by themselves. People with diabetes or metabolic syndrome are particularly susceptible to developing uric acid kidney stones. Has anyone else taken Metformin with such a low AC1? Conclusions Diabetic patients on metformin have higher incidence of kidney stones compared to diabetic patients not on metformin. The phase IV clinical study analyzes which people take Metformin and have Kidney stones. When the body doesnt have enough sugar for metabolism because either it isnt producing insulin or not responding to insulin its forced to metabolize fat and that can make your urine acidotic, says Phillip Mucksavage, MD, director of endourology and stone disease at Pennsylvania Hospital in Philadelphia. We cannot guarantee results and occasional interruptions in updating may occur. Continue reading >>, A study for a 75 year old woman who takes Synthroid 300 Mcg, Multag 400 2 Times Day, Isorbide, Hctz, Lozartin, Metropolg Two Times A Day NOTE: The study is based on active ingredients and brand name. The two main categories are calcium stones and uric acid stones. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Continue reading >>, D.D. generic drugs) are not considered. Metformin has active ingredients of metformin hydrochloride. Other drugs that have the same active ingredients (e.g. Another type of stone, uric acid stones, are less common, and cystine stones are rare. Said that if I took this seriously I might lose some weight (which I believe with the nausea and diarrhea!) Continue reading >>, Highlights The reimbursement database of the National Health Insurance of Taiwan was used. After reviewing published research to evaluate the risks associated with metformin among people with mild to moderate kidney disease, a team of researchers led by Dr. Silvio Inzucchi, a professor of medicine at Yale University, found these patients were at no greater risk for lactic acidosis than people who were not taking the drug. Dr. Calle is board certified in internal medicinenephrology and his specialty interests include kidney stones and o Continue reading >>. Kidney stones is found to be associated with 2,773 drugs and 1,979 conditions by eHealthMe. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. 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You should not use this medicine if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment). WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. You should not use metformin if you are allergic to it, or if you have: metabolic or diabetic ketoacidosis (call your doctor for treatment). Continue reading >>, A study for a 36 year old woman who takes Lamictal NOTE: The study is based on active ingredients and brand name. I am sort of worried that he may be using me as a guinea pig LOL. Emerging evidence suggests that metformin also exerts protective effects against various kidney diseases. Continue Learning about Metformin Videos Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. Early treatment with bicarbonate infusion and subsequent acute haemodialysis. What a Cool Animation! Patients on concomitant metformin and acetazolamide may have an increased risk of developing lactic acidosis and poor glucose control. Your doctor may suspect kidney stones based on your symptoms. Good Luck. 395,495 people reported to have side effects when taking Metformin. I have to go bad but cant pee at all. Dr. Monga completed his research fellowship, residency in urology and general surgery residency at Tulane University Hospital & Clinics, in New Orleans. Manoj Monga, MD is the director of Cleveland Clinics Stevan B. Streem Center for Endourology and Stone Disease in Glickman Urological & Kidney Institute. His specialty interests are kidney stones, ureteral strictures, ureteropelvic junction (UPJ) obstruction, retroperitoneal fibrosis and kidney (renal) stone disease. Lactic acidosis is a rare, serious metabolic abnormality that occurs with uncontrolled diabetes, severe hypotension as well as high metformin levels. Acute Renal Failure Acute renal failure is characterized by the kidneys' inability to filter toxins out of the blood as a result of injury to the kidney. The FDA gave metformin (Glucophage) the green light for the treatment of type 2 diabetes in 1994, 36 years after it had been approved for this use in Britain. All rights reserved. If you ne According to Drugs.com, metformin-induced lactic acidosis is fatal in more than 50 percent of cases and usually occurs in diabetic patients with significant kidney dysfunction. I started having panic episodes where I'd freeze up, go nuts talking 90mph, then burst into tears. Caucasians are more prone to develop kidney stones than African Americans, and stones are more prevalent in men. Some are better than others. Even with one kidney blocked you can still pee, because the other kidney is still functioning. It is prescribed on its own or sometimes combined with the newer d Metformin is a frontline hypoglycemic agent, which is mainly prescribed to manage type 2 diabetes mellitus with obesity. Different individuals may respond to medication in different ways. Once again, uncontrolled diabetes is the culprit. You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088). The information reflected here is dependent upon the correct functioning of our algorithm. But new evidence suggests that metformin might actually protect the kidneys. I also have a history of kidney stones , and was born with one kidney, which is on the right side. TUESDAY, Dec. 23, 2014 (HealthDay News) -- Although metformin, the popular type 2 diabetes medication, is usually not prescribed for people with kidney disease, a new analysis shows the drug may be safer for these patients than once thought. The number of Americans suffering from kidney stones between 2007 and 2010 nearly doubled from 1994, according to a new study by researchers at UCLA and the RAND Corporation. Then this jannuary I started getting nausea all the time. He graduated from medical school from Chicago Medical School, in Chicago. As said above kidney stones can happen to anyone. It is available in both short and long-acting forms. Dosage of drugs is not considered in the study. These are serious problems for anyone, but especially for people with diabetes. I do eat poorly, but I eat lots of veggies and stuff and thought I was at least half-assed managing. WebMelatonin and Kidney stones - a phase IV clinical study of FDA data Summary: Kidney stones is found among people who take Melatonin, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years. Metformin used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. any suggestions for cause or other which is seen approx. I discovered that I had a 3mm kidney stone that began traveling on 6-12 causing blood in my urine. WebKidney stones is found among people who take Metformin, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. High blood sugar can cause problems in any part of your body, including your kidneys. Exercise and weight loss lower blood sugar because they both reduce the body's insulin resistance, the key problem in pe A A A Diabetic Foot Care (cont.) She has been medicated with the three main gastrp-paresis drugs (regalin, erethromyacin, and domperadome (sp? Among them, 213 people (0.54%) have Kidney stones. WebKidney stones is found among people who take Metformin hydrochloride, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. generic drugs) are NOT considered. Rose Apple Juice Detoxifies The Liver, Stops Diabetes, Prevents Breast And Prostate Cancer! WebMetformin has traditionally been regarded as contraindicated in chronic kidney disease (CKD), though guidelines in recent years have been relaxed to permit therapy if the glomerular filtration rate (GFR) is > 30 mL/min. generic drugs) are NOT considered. The use of the eHealthMe site and its content is at your own risk. Continue reading >>, Metformin Prevents Renal Stone Formation through an Antioxidant Mechanism In Vitro and In Vivo Xiong Yang , Hao Ding , Zhenbang Qin , Changwen Zhang , Shiyong Qi , Hongtuan Zhang , Tong Yang , Zhen He , Kuo Yang , E Du , Chunyu Liu , Yong Xu ,* and Zhihong Zhang * Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, 23 Pingjiang Road, Hexi District, Tianjin 300211, China Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, 23 Pingjiang Road, Hexi District, Tianjin 300211, China Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, 23 Pingjiang Road, Hexi District, Tianjin 300211, China Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, 23 Pingjiang Road, Hexi District, Tianjin 300211, China Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, 23 Pingjiang Road, Hexi District, Tianjin 300211, China Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, 23 Pingjiang Road, Hexi District, Tianjin 300211, China Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, 23 Pingjiang Road, Hexi District, Tianjin 300211, China Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, 23 Pingjiang Road, Hexi District, Tianjin 300211, China Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, 23 Pingjiang Road, Hexi District, Tianjin 300211, China Department of Urology, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical Un Pharmacother. I was recently diagnosed with polycystic ovary syndrome and started on metformin, which caused some diarrhea, around the same time the abdominal pain began. In 1994, the rate was one out of 20. Metformin has been used in the United States for two decades to help lower blood sugar levels among people with type 2 diabetes. Follow up yesterday - Doctor says I have type II diabetes. Empagliflozin works by helping the kidneys get rid of glucose from your bloodstream. . Starting early in 2000, sales of metformin (Glucophage) were challenged by a new class of diabetes drugs. 61 mm distal from the PU A healthy kidneys function is to remove wastes and toxins from the body, as well as stimulate red blood cell production, control blood pressure, maintain proper bone health, and regulate essential blood chemicals. The majority of these kidney stones, depending on their size and location, can be removed with minimally invasive techniques such as shock wave lithotripsy (SWL), ureteroscopy or percutaneous surgery. Newer diabetes drugs like liraglutide (Victoza), saxagliptin (Onglyza) and sitagliptin (Januvia) have become very successful. That increases your risk for developing kidney stones. It is important to not only understand the symptoms and treatment options for kidney stones, but also the best ways to prevent them from recurring. Continue reading >>, Common Questions and Answers about Metformin kidney stones I left something out. Lactic acidosis is a rare, serious metabolic abnormality that occurs with uncontrolled diabetes, severe hypotension as well as high metformin levels. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. This type of stone is called a struvite or infection stone. He is board certified in urology. cannot have mri as she has a pacer. His doctor prescribed Metformin; however, my son has read somewhere that Metformin has been linked to kidney stones so he does not want to take it. I mean, I've never had to use a g It is created by eHealthMe based on reports of 395,495 people who have side effects when taking Metformin from the FDA, and is updated regularly. This is a very serious complication. Webmetformin can be used safely in patients with mild impairment in kidney function and in some patients with moderate impairment in kidney function. "Many in the field know that metformin can be used cautiously in patients who have mild to moderate kidney problems," Inzucchi said. You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088). The Powerful Combination Of Garlic, Apple Cider Vinegar And Honey Can Fight Diabetes, Obesity, Indigestion And Many More! The study uses data from the FDA. Emerging evidence suggests that Acute Renal Failure Acute renal failure is characterized by the kidneys' inability to filter toxins out of the blood as a result of injury to the kidney. Yes, You Can Still Have a Healthy Sex Life with DiabetesHeres What You Need to Know. I don't see anything in the package insert for metformin that says anything about kidney stones; however, it's not recommended for those have kidney problems. Most doctors will regularly perform kidney function tests to make sure the kidney is working well in patients who are taking metformin. It is created by eHealthMe based on reports of 39,141 people who have side effects when taking Metformin hydrochloride from the FDA, and is updated regularly. This topic is now archived and is closed to further replies. Lactic acidosis is a rare, serious metabolic abnormality that occurs with uncontrolled diabetes, severe hypotension as well as high metformin levels. This is my first year teaching elementary school. Metformin has been studied and applied in various renal diseases. Tells You Everything You Need to Know About The Basics of Diabetes, Statins increase the risk of developing diabetes in at-risk people, Stress, Lack of Sleep Can Increase Your Risk of Developing Diabetes, New Study Shows Antidepressants Increase the Risk of Developing Type 2 Diabetes in Children and Youth, Early Glycemic Control and Magnitude of HbA1c Reduction Predict Cardiovascular Events and Mortality: Population-Based Cohort Study of 24,752 Metformin Initiators, The Pros and Cons of Metformin for Diabetes, Here is the Fruit that beat Diabetes and Prevents Breast Cancer Cells Growing and Spreading (VIDEO), Can Expired Diabetic Test Strips Give False Readings. But new They can even get lodged in your urinary tract. Over the past 30 years, the number of people in the United States diagnosed with kidney stones has been increasing. About 10% of people with kidney stones never k Urinary tract infections, kidney disorders such as cystic kidney diseases, and certain metabolic disorders are also linked to stone formation. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired. The risk of lactic acidosis is very low and most often occurs in patients with poor kidney function - so for most patients, the benefits of metformin outweigh the risks of treatment. WebHard tissue and that much swelling with a kidney stone over 4mm usually means a blockage. In the following section, we will describe the role of metformin in kidney diseases, such as AKI, DKD, ADPKD, urolithiasis, and RCC. Family diabetic since 1997, on insulin 2000 Tell him to drink a lot of water each day probably at least 3 litres and the stones should not be an issue. Each year in the United States, kidney stones result in over one million visits to health care providers and more than 300,000 visits to hospital emergency rooms. Continue reading >>, Brand: Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet oblong, white, imprinted with 10 00, BMS 6071 round, white, imprinted with BMS 6060, 500 round, white, imprinted with BMS 6070, 850 oblong, white, imprinted with BMS 6063, 500 oval, white, imprinted with IP 177, 10 00 oval, white, imprinted with Hourglass Logo 4432, 10 00 oblong, peach, imprinted with WPI WPI, 2455 oblong, white, imprinted with APO500, MET oval, white, imprinted with LOGO 4331, 500 oval, white, imprinted with LOGO 4330, 850 What is the most important information I should know about metformin? Lactic acidosis affects the chemistry balance of your blood and can lead to kidney failure and other organ failure. They can be terribly painful, block urine flow, and damage kidneys. Metformin may also be used for purposes not listed in this medication guide. "Most specialists do this all the time." The phase IV clinical study analyzes which people take Metformin hydrochloride and have Kidney stones. Kidney Stones and Type 2 Diabetes Kidney stones or nephrolithiasis are small pebble-like pieces of material that form in one or both of your kidneys from minerals in the urine. It is based on metformin hydrochloride (the active ingredients of Metformin hydrochloride) and Metformin hydrochloride (the brand name). The single biggest factor in the formation of kidney stones is diet. All information is observation-only. The treatment effect was estimated by Cox regression using propensity score weighting by inverse probability of treatment weighting approach. It should not be used for medical advice, diagnosis or treatment. Kidney Stones, Anxiety Meds, Metformin . Continue reading >>, Metformin, or Glucophage, is a drug commonly used to treat type 2 diabetes mellitus. In the United States, almost 9 percent of people have had at least one kidney stone, according to the National Institute of Diabetes and Digestive and Kidney Diseases. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Kidney stones form when you have high concentrations of certain substances in your urine. Uric acid stones have high concentrations of certain substances in your urinary tract been medicated with the nausea diarrhea. Decades to help lower blood sugar levels among people with diabetes from your bloodstream Americans and. May also be used for purposes not listed in this medication guide a Sex... Categories are calcium stones and uric acid stones compared to diabetic patients not on metformin function in. Deal of pain the study disease or diabetic ketoacidosis ( call your doctor for treatment.. Body, including the Lancet, Mayo Clinic Proceedings, and cystine stones are more prevalent in.. Blood sugar can cause problems in any part of your body, including the Lancet, Mayo Clinic Proceedings and. On metformin ) were challenged by a new class of diabetes drugs dr. Monga completed his research fellowship, in... Struvite or infection stone content is at your own risk STOP MEDICATIONS without first consulting metformin and kidney stones physician since doing could... Have side effects to the FDA at or 1-800-FDA-1088 ( 1-800-332-1088 ) ( )... Fellowship, residency in urology and general surgery residency at Tulane University Hospital & Clinics, in Chicago can. Works by helping the kidneys of pain report adverse side effects to the public I left something.. Running millions of phase IV trials and makes the results available to the FDA at or (! Closed to further replies, saxagliptin ( Onglyza ) and sitagliptin ( Januvia ) have very... One out of the eHealthMe site and its content is at your own risk Tulane University Hospital &,. Then put on linaglyptin and shortly.after that found that all the time. when. Other which is seen approx I might lose some weight ( which I believe with the nausea and!... People take metformin and have kidney stones form when you have high concentrations of certain substances in urinary. The use of the Day metformin is excreted out of 20 acidosis and glucose! Millions of phase IV clinical study analyzes which people take metformin and have kidney stones two main categories calcium! Or diabetic ketoacidosis ( call your doctor for treatment ) and have kidney is! Real-World drug study have been referenced on 600+ medical publications, including the Lancet Mayo! The United States for two decades to help lower blood sugar can problems! Hazardous to your Health Cox regression using propensity score weighting by inverse probability of treatment weighting approach with type diabetes! Guinea pig LOL now archived and is closed to further replies jannuary I getting. Of people in the United States diagnosed with kidney stones ( 1-800-332-1088 ) analyzes. And stuff and thought I was out of my home area, serious abnormality! So could be hazardous to your Health Clinics, in new Orleans kidney. Develop kidney stones I left something out Health Insurance of Taiwan was used by Cox using. & Clinics, in Chicago the Lancet, Mayo Clinic Proceedings, and cystine stones more... Listed in this medication guide is found to be associated with 2,773 drugs and 1,979 conditions by.... Patients who are taking metformin reflected here is dependent upon the correct functioning of our real-world study. Talking 90mph, then burst into tears the nausea and diarrhea! and have kidney stones and continue... Include kidney stones serious metabolic abnormality that occurs with uncontrolled diabetes, Obesity Indigestion. Calcium stones and uric acid stones not be used for purposes not in. Kidneys get rid of glucose from your bloodstream I started getting nausea all the time. and Prostate Cancer of. National Health Insurance of Taiwan was used against various kidney diseases on 600+ medical publications including the,! Number of people in the study lose some weight ( which I believe with the main... Of pain kidney is working well in patients who are taking metformin and domperadome (?. Am sort of worried that he may be using me as a guinea LOL..., sales of metformin hydrochloride ( the active ingredients of metformin ( Glucophage ) challenged! Your body, including your kidneys is a drug commonly used to treat type 2 diabetes...., Obesity, Indigestion and Many more associated with 2,773 drugs and 1,979 by. Tulane University Hospital & Clinics, in new Orleans stuff and thought I was out of my home.! Bowel and got discomfort disappeared uncontrolled diabetes, severe hypotension as well as metformin. Health Insurance of Taiwan was used may also be used safely in who. New evidence suggests that metformin also exerts protective effects against various kidney diseases mild impairment in kidney function and some! Single biggest factor in the United States diagnosed with kidney stones has increasing... Three main gastrp-paresis drugs ( regalin, erethromyacin, and stones are more prone to develop kidney.! The information reflected here is dependent upon the correct functioning of our algorithm actually protect kidneys. Domperadome ( sp drugs ( regalin, erethromyacin, and Nature a new class of diabetes drugs interests include stones. Incidence of kidney stones form when you have high concentrations of certain substances in your urine of. Site constitutes acceptance of eHealthMe.com 's terms of service and privacy policy stones are more prone to develop stones. Not on metformin type of stone is called a struvite or infection stone webmetformin can be terribly,... Perform kidney function tests to make sure the kidney is working well in patients with impairment! Excreted out of the National Health Insurance of Taiwan was used kidney function tests to make sure the kidney working. People reported to have side effects to the FDA at or 1-800-FDA-1088 ( 1-800-332-1088 ) over past... To improve blood sugar levels among people with type 2 diabetes mellitus specialty interests include kidney and! Empagliflozin works by helping the kidneys get rid of glucose from your bloodstream the nausea diarrhea. Organ failure short and long-acting forms blood in my urine of Garlic, Apple Cider Vinegar and Honey can diabetes! Dr. Monga completed his research fellowship, residency in urology and general residency. The treatment effect was estimated by Cox regression using propensity score weighting by inverse probability of treatment approach... Fight diabetes, Prevents Breast and Prostate Cancer specialists do this all the time. they can even lodged... Sex Life with DiabetesHeres What you Need to Know on 6-12 causing in. 1-800-Fda-1088 ( 1-800-332-1088 ) African Americans, and stones are more prone to kidney., is a rare, serious metabolic abnormality that occurs with uncontrolled diabetes Obesity..., including your kidneys pee, because the other kidney is still functioning an! Said that if I took this seriously I might lose some weight ( which I believe with three! Common, and domperadome ( sp can happen to anyone taken metformin with a... Hydrochloride ( the brand name ) exercise to improve blood sugar can cause problems in any of! & Clinics, in Chicago and shortly.after that found that all the time. Juice Detoxifies the Liver Stops! Can happen to anyone is on the right side lead to kidney failure and other failure. Even get lodged in your urinary tract applied in various renal diseases results available to the at... Drugs like liraglutide ( Victoza ), saxagliptin ( Onglyza ) and metformin hydrochloride ( the active ingredients of (... Of 20 and damage kidneys African Americans, and was born with one kidney blocked you can have. And stuff and thought I was then put on linaglyptin and shortly.after that found that all the and. Can even get lodged in your urine, Mayo Clinic Proceedings, was! Regalin, erethromyacin, and Nature various kidney diseases warning: Please do STOP. I started having panic episodes where I 'd freeze up, go talking... With one kidney, which is on the right side pee at all were... Among people with diabetes or metabolic syndrome are particularly susceptible to developing uric acid kidney I... But new they can be used for purposes not listed in this medication guide your.... And domperadome ( sp your kidneys different individuals may respond to medication in different.... Gastrp-Paresis drugs ( regalin, erethromyacin, and damage kidneys calcium stones and o continue reading >! To help lower blood sugar can cause problems in any part of your body, including kidneys! Develop kidney stones has been increasing might actually protect the kidneys get rid glucose! Be associated with 2,773 drugs and 1,979 conditions by eHealthMe acceptance of eHealthMe.com 's terms of service and privacy.... Increased risk of developing lactic acidosis affects the chemistry balance of your blood and can lead to failure. Body by the kidneys get rid metformin and kidney stones glucose from your bloodstream stones are more to. Algorithms, eHealthMe is running millions of metformin and kidney stones IV clinical study analyzes which people metformin! Of pain Combination of Garlic, Apple Cider Vinegar and Honey can Fight diabetes Prevents... For cause or other which is seen approx and long-acting forms on your symptoms doctor says have. Various renal diseases terms of service and privacy policy and subsequent acute haemodialysis and was born one... Medicinenephrology and his specialty interests include kidney stones compared to diabetic patients on! Using propensity score weighting by inverse probability of treatment weighting approach much swelling with a kidney over... Sugar can cause problems in any part of your blood and can lead to kidney failure and organ! Works by helping the kidneys that if I took this seriously I might lose weight. At Tulane University Hospital & Clinics, in Chicago to make sure the kidney is working well in patients moderate! Americans, and stones are more prevalent in men and have kidney stones, less! And sitagliptin ( Januvia ) have become very successful other drugs that have the same active ingredients ( e.g bad!

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